翻訳と辞書
Words near each other
・ Base defense operations center
・ Base Details
・ Base effect
・ Base end station
・ Base Erosion and Profit Shifting
・ Base excess
・ Base Exchange
・ Base excision repair
・ Base fee
・ Base Feeder
・ Base flow
・ Base flow (random dynamical systems)
・ Base FX
・ Base General Bernardo O'Higgins Riquelme
・ Base isolation
Base J
・ Base Jumpers
・ BASE jumping
・ Base level
・ Base Line, Little Rock
・ Base load power plant
・ Base locus
・ Base metal
・ Base modifying agent
・ Base Mérimée
・ Base of fire
・ Base of lung
・ Base of skull
・ Base of the sacrum
・ Base oil


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Base J : ウィキペディア英語版
Base J

β-D-Glucopyranosyloxymethyluracil or base J is a hypermodified nucleobase found in the DNA of kinetoplastids including the human pathogenic trypanosomes. It was discovered in 1993, in the trypanosome ''Trypanosoma brucei'' and was the first hypermodified nucleobase found in eukaryotic DNA; it has since been found in other kinetoplastids, including ''Leishmania''.
Within these organism Base J acts as a RNA polymerase II transcription terminator, with its removal in knockout cells being accompanied by a massive read-through at RNA polymerase II termination sites, which ultimately proves lethal to the cell.
Base J is formed by the initial hydroxylation of thymidine and the subsequent glycosylation by an as yet unidentified glycosyltransferase.
]
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Base J」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.